Products - Stemgent - Reprogramming the Reagent

Viruses
Kits / Sets
Stemgent^® Dox Inducible Reprogramming Lentivirus Kit: Mouse OKSM , Cat. No. 00-0024 The Stemgent® Mouse iPSC Generation Kit is fully validated and designed to simplify and facilitate the production of mouse induced pluripotent stem cells. The iPSC Generation Dox Inducible Mouse TF Lentivirus Set: OKSM + RG includes each of the four mouse transcription factors (Oct4, Klf4, Sox2, and c-Myc) and is able to reprogram the provided Oct4-neo mouse embryonic fibroblasts (MEFs) (P2) to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell. The expression of these four factors, along with the reverse tetracycline transcriptional activator (rtTA), has been shown to reprogram MEFs to iPS cells. In addition, the Mouse ES/iPS Cell Characterization Set contains all the antibodies (SSEA-1, Nanog, and Oct4) and the Alkaline Phosphatase Staining Kit to fully characterize mouse iPS and ES cells.	1 Kit with 4 components $2499.00
iPSC Generation Components
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Klf4 , Cat. No. ST070033-1ml The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Klf4 provides the human transcription factor Klf4 for use with Sox2, Oct4, and c-Myc to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	1 ml $299.00
Stemgent^® Reprogramming Lentivirus: Human c-Myc , Cat. No. ST070014-1ml The Stemgent^® Reprogramming Lentivirus: Human c-Myc provides an affordable method for generating iPS cells. The hc-Myc lentivirus, along with the hOct4, hKlf4, and hSox2 prepackaged lentivirus, is tested and proven to reprogram human fibroblast cells.	1 ml $199.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human c-Myc (conc) , Cat. No. ST070038-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human c-Myc (conc) provides the human transcription factor c-Myc for use with Sox2, Oct4, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	100 μl $599.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Sox2 (conc) , Cat. No. ST070002-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Sox2 (conc)provides the mouse transcription factor mSox2 for use with Oct4, c-Myc and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	100 μl $599.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Oct4 (conc) , Cat. No. ST070003-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Oct4 (conc) provides the mouse transcription factor mOct4 for use with Sox2, c-Myc and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	100 μl $599.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Klf4 (conc) , Cat. No. ST070005-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Klf4 (conc) provides the mouse transcription factor mKlf4 for use with Sox2, Oct4 and c-Myc to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	100 μl $599.00
Stemgent^® Reprogramming Lentivirus: Human Nanog , Cat. No. ST070017 The Stemgent^® Reprogramming Lentivirus: Human Nanog, along with Oct4, Sox2, and Lin28, enables reprogramming of somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	1 ml $199.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse Klf4 , Cat. No. ST070010 The Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse Klf4, along with Oct4, Sox2, and c-Myc, provides an affordable inducible method for generating iPS cells.	1 ml $299.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse c-Myc (conc) , Cat. No. ST070004-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse c-Myc (conc) provides the mouse transcription factor mc-Myc for use with Sox2, Oct4 and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	100 μl $599.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Mouse c-Myc , Cat. No. ST070009 The Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse c-Myc , along with Sox2, Oct4, and Klf4, provides an affordable inducible method for generating iPS cells.	1 ml $299.00
Stemgent^® Reprogramming Lentivirus: Human Klf4 , Cat. No. ST070015-1ml Stemgent® Reprogramming Lentivirus: Human Klf4 provides an affordable method for generating iPS cells. The hKlf4 lentivirus, along with the hOct4, hc-Myc, and hSox2 prepackaged lentivirus, is tested and proven to reprogram human fibroblast cells.	1 ml $199.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human c-Myc , Cat. No. ST070034-1ml The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human c-Myc provides the human transcription factor c-Myc for use with Sox2, Oct4, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	1 ml $299.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Klf4 (conc) , Cat. No. ST070037-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Klf4 (conc) provides the human transcription factor Klf4 for use with Sox2, Oct4, and c-Myc to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	100 μl $599.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Oct4 , Cat. No. ST070031-1ml The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Oct4 provides the human transcription factor Oct4 for use with Sox2, c-Myc, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	1 ml $299.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Oct4 (conc) , Cat. No. ST070035-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Oct4 (conc) provides the human transcription factor Oct4 for use with Sox2, c-Myc, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	100 μl $599.00
Stemgent^® Reprogramming Ecotropic Retrovirus: Mouse Oct4 , Cat. No. 07-0042 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The Oct4 retrovirus, along with Sox2, Klf4, and c-Myc, is capable of expressing the mouse reprogramming factors when transduced into mouse and rat cells.	250 µl $99.00
Stemgent^® Reprogramming Ecotropic Retrovirus: Mouse Klf4 , Cat. No. 07-0043 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The Oct4 retrovirus, along with Sox2, Klf4, and c-Myc, is capable of expressing the mouse reprogramming factors when transduced into mouse and rat cells.	250 µl $99.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Sox2 , Cat. No. ST070032-1ml Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Sox2 provides the human transcription factor Sox2 for use with Oct4, c-Myc, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	1 ml $299.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Sox2 (conc) , Cat. No. ST070036-100ul The Stemgent^® Dox Inducible Reprogramming Lentivirus: Human Sox2 (conc) provides the human transcription factor Sox2 for use with Oct4, c-Myc, and Klf4 to reprogram somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell.	100 μl $599.00
Stemgent^® Reprogramming Ecotropic Retrovirus: Mouse c-Myc , Cat. No. 07-0045 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The c-Myc retrovirus, along with Oct4, Klf4, and Sox2, is capable of expressing the mouse reprogramming factors when transduced into mouse and rat cells.	250 µl $99.00
Stemgent^® Reprogramming Ecotropic GFP Retrovirus , Cat. No. 07-0046 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The GFP retrovirus serves as a convenient transduction control when used to transduced mouse and rat cells.	250 µl $99.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse Oct4 , Cat. No. ST070008 The Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse Oct4, along with Sox2, c-Myc, and Klf4, provides an affordable inducible method for generating iPS cells.	1 ml $299.00
Stemgent^® Reprogramming Lentivirus: Human Oct4 , Cat. No. ST070013 The Stemgent^® Reprogramming Lentivirus: Human Oct4 , along with Sox2, Lin28 and Nanog, enables reprogramming of somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	1 ml $199.00
Stemgent^® Reprogramming Lentivirus: Human Sox2 , Cat. No. ST070012 The Stemgent^® Reprogramming Lentivirus: Human Sox2 , along with Oct3/4, Lin28 and Nanog, enables reprogramming of somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	1 ml $199.00
Stemgent® Dox Inducible Reprogramming Lentivirus Set: Human OKSM (conc) , Cat. No. 00-0012 The Stemgent® iPSC Generation Dox Inducible Human TF Lentivirus Set: OKSM (Concentrated) provides an affordable inducible method for generating iPS cells. The set includes hOct4, hSox2, hc-Myc, and hKlf4 transcription factors as prepackaged lentivirus particles tested and proven to reprogram human fibroblast cells.	4 x 100 μl $1999.00
Stemgent^® Reprogramming Lentivirus: Human Lin28 , Cat. No. ST070016-1ml The Stemgent® Reprogramming Lentivirus: Human Lin28, along with Oct3/4, Sox2, and Nanog, enables reprogramming of somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	1 ml $199.00
Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse Sox2 , Cat. No. ST070007 The Stemgent^® Dox Inducible Reprogramming Lentivirus: Mouse Sox2, along with Oct4, c-Myc, and Klf4, provide an affordable inducible method for generating iPS cells.	1 ml $299.00
Stemgent^® Reprogramming Ecotropic Retrovirus: Mouse Sox2 , Cat. No. 07-0044 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The Sox2 retrovirus, along with Oct4, Klf4, and c-Myc, is capable of expressing the mouse reprogramming factors when transduced into mouse and rat cells.	250 µl $99.00
iPSC Generation Kits / Sets
Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Human OKSM (conc.) , Cat. No. ST000037-1Set The Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Human OKSM (conc) provides an affordable inducible method for generating iPS cells. The set includes hOct4, hSox2, hc-Myc, hKlf4, GFP, and the reverse tetracycline transcriptional activator, rtTA, as prepackaged lentivirus particles tested and proven to reprogram human fibroblast cells. Each unique virus is provided as a VSV-G pseudotyped and concentrated virus stock capable of infecting both dividing and non-dividing cells. The expression of the four factors, in conjunction with rtTA, has been shown to direct a variety of differentiated cell types to become reprogrammed iPS cells.	1 set $2999.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Human OKSM , Cat. No. ST000036-1Set The Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Human OKSM provides an affordable inducible method for generating iPS cells. The set includes hOct4, hSox2, hc-Myc, and hKlf4 transcription factors and rtTA and GFP as prepackaged as lentivirus particles tested and proven to reprogram human fibroblast cells. Each unique virus is provided as a VSV-G pseudotyped virus stock capable of infecting both dividing and non-dividing cells. The expression of the four factors, in conjunction with rtTA, has been shown to direct a variety of differentiated cell types to become reprogrammed iPS cells1.	1 set $1499.00
Stemgent^® Reprogramming Lentivirus Set: Human OKSM , Cat. No. ST000044-1Set The Stemgent^® Reprogramming Lentivirus Set: Human OKSM provides an affordable method for generating iPS cells. The set includes hOct4, hSox2, hc-Myc, and hKlf4 transcription factors as prepackaged lentivirus particles tested and proven to reprogram human fibroblast cells.	1 set $649.00
Stemgent® Reprogramming Adenovirus Set: Mouse OKSM , Cat. No. 00-0008 The Stemgent® Reprogramming Adenovirus Set: Mouse OKSM provides the mouse transcription factors Oct4, Sox2, Klf4, c-Myc, and GFP for use in reprogramming somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	5 x 100 μl $599.00
Stemgent® Reprogramming Ecotropic Retrovirus Kit: Mouse OSKM , Cat. No. 00-0049 The Stemgent® Reprogramming Ecotropic Retrovirus Kit: Mouse OSKM is a complete kit that has been validated for the generation and characterization of mouse induced pluripotent stem (iPS) cells.	1 Kit with 3 components $1899.00
Stemgent® Reprogramming Ecotropic Retrovirus Set: Mouse OKSM , Cat. No. 00-0042 The Stemgent® iPSC Generation Mouse TF Ecotropic Retrovirus Set: OKSM + G provides an affordable method for generating iPS cells. The set consists of four retroviruses, each of which is capable of expressing one of four transcription factors (Oct4, Klf4, Sox2, and c-Myc) when transduced into mouse and rat cells.	10 vials per set, 2 vials of each virus $649.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Mouse OKSM (conc) , Cat. No. 00-0003 The Stemgent™ Dox Inducible Mouse TF Lentivirus Set provides the mouse transcription factors Oct4, Sox2, c-Myc and Klf4 for use in inducible reprogramming of somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	4 x 100 μl $1999.00
Stemgent^® Dox Inducible Reprogramming Polycistronic Lentivirus Set: Mouse 4F2A (2 rxn) , Cat. No. ST000043-1Set The Stemgent^® Dox Inducible Reprogramming Polycistronic Lentivirus Set: Mouse 4F2A (2 rxn) offers the four mouse transcription factors (Oct4, Sox2, Klf4 or c-Myc) within a single, polycistronic expression cassette that has been tested and proven to reprogram mouse somatic cells into iPS cells.	1 set $1999.00
Stemgent® Dox Inducible Reprogramming Lentivirus Set: Human OKSM , Cat. No. 00-0011 The Stemgent® iPSC Generation Dox Inducible Human TF Lentivirus Set: OKSM provides an affordable inducible method for generating iPS cells. The set includes hOct4, hSox2, hc-Myc, and hKlf4 transcription factors as prepackaged lentivirus particles tested and proven to reprogram human fibroblast cells.	4 x 1 ml $999.00
Stemgent® Dox Inducible Reprogramming Lentivirus Set: Mouse OKSM , Cat. No. 00-0004 The Stemgent™ iPSC Generation Dox Inducible Mouse TF Lentivirus Set: OSKM provides an affordable inducible method for generating iPS cells. The set includes mOct4, mSox2, mc-Myc, and mKlf4 transcription factors as prepackaged lentivirus particles tested and proven to reprogram mouse somatic cells.	4 x 1 ml $999.00
Stemgent® Dox Inducible Reprogramming Polycistronic Lentivirus Kit: Mouse 4F2A , Cat. No. 00-0050 The Stemgent® Dox Inducible Reprogramming Polycistronic Lentivirus Kit: Mouse 4F2A is a complete kit with a polycistronic 4F2A lentivirus that has been validated for the generation and characterization of mouse induced pluripotent stem (iPS) cells.	1 kit with 4 components $2999.00
Small Molecules
Stemolecule™ XAV939 , Cat. No. 04-0046 Stemolecule™ XAV939 inhibits the Wnt / β-catenin pathway. Current research suggests that Wnt proteins act to maintain stem cells in an undifferentiated, self-renewing state. Wnt proteins act on a variety of stem cells that include neural, mammary and embryonic stem cells. XAV939 also inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.	2 mg $239.00
Stemolecule™ Pifithrin-α , Cat. No. 04-0038 Stemolecule™ Pifithrin-α (PFT-α) is a small molecule inhibitor of p53 dependent apoptosis and transcriptional activation for cyclin G, p21/waf1, and mdm2 expression. The reduction of p53 activity has been shown to enhance reprogramming efficiency of human and mouse somatic cells.	5 mg $99.00
Stemolecule™ Pifithrin-μ , Cat. No. 04-0039 Stemolecule^™ Pifithrin-µ inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. The mechanism of action of PFT-µ is different from PFT-α since PFT-µ inhibits the p53 mitochondrial pathway but does not affect any additional transcriptional functions of p53. The reduction of p53 activity has been shown to enhance reprogramming efficiency of human and mouse somatic cells. PFT-µ rescues cells from lethal γ-irradiation induced cell death and protects mice from doses of radiation that cause lethal hematopoietic syndrome.	5 mg $69.00
Stemolecule™ KAAD-Cyclopamine , Cat. No. 04-0028 Stemolecule™ KAAD-Cyclopamine is a sonic hedgehog antagonist known to target Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. KAAD-Cyclopamine has been utilized to halt the migration or proliferation of a variety of cancer cells.	100 μg $249.00
Stemolecule™ Ku-0063794 , Cat. No. 04-0050 Stemolecule™ Ku-006379 is an inhibitor of the mammalian target of rapamycin (mTOR). Ku-0063794 suppresses cell growth and induces a G1 cell cycle arrest by inhibiting two mTOR complexes, mTOR1 and mTOR2, but does not inhibit a large number of other protein kinases. Since mTOR positively affects protein synthesis and consequently affects both cell survival and cell proliferation, Stemolecule™ Ku-0063794 may be useful in studies in these areas.	2 mg $179.00
Stemolecule™ IPA-3 , Cat. No. 04-0037 Stemolecule™ IPA-3 is an allosteric inhibitor of Pak kinase activation. IPA-3 also inhibits the activation of related Pak kinase isoforms, but not more distantly related Pak kinases or other kinases. IPA-3 binds covalently to the Pak1 regulatory domain and prevents binding to the upstream activator Cdc42.	5 mg $79.00
Stemolecule™ IDE-2 , Cat. No. 04-0027 Stemolecule™ IDE-2 is an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells in mouse and human ES cell cultures¹. IDE-2 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.	2 mg $239.00
Stemolecule™ IDE-1 , Cat. No. 04-0026 Stemolecule™ IDE-1 is an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells in mouse and human ES cell cultures. Endoderm chemically induced by IDE-1 can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.	2 mg $239.00
Stemolecule™ Forskolin , Cat. No. 04-0025 Stemolecule™ Forskolin can potentiate neuron differentiation and can also stimulate adenylate cyclase activity and increase cyclic AMP. Protein kinase A (PKA) activity is dependent upon binding to cAMP and has been implicated in sonic hedgehog signaling.	10 mg $149.00
Stemolecule™ GSK429286A , Cat. No. 04-0049 Stemolecule™ GSK429286A inhibits Rho-associated, coiled-coil containing protein kinase (ROCK). ROCKs are serine/threonine specific protein kinases which play a crucial role in organization of the actin cytoskeleton. ROCK inhibitors have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency. Because of GSK429286A’s specificity, this reagent may be useful in assessing the cellular roles of individual ROCK isoforms.	2 mg $249.00
Stemolecule™ Doxycycline hyclate , Cat. No. 04-0016 Stemolecule™ Doxycycline hyclate (Dox), a derivative of tetracycline, is used to induce expression of the Stemgent® iPSC Generation Dox Inducible products. In the iPSC Generation Dox Inducible protocol, addition of Dox to the culture medium of transduced cells induces the reverse tetracycline transactivator (rtTA) to bind to the Tet response element and results in the transcriptional activation for each of the factors implicated in the reprogramming process. Conversely, Dox can be removed from the medium to suppress transcriptional activation of the reprogramming factors.	10 mg $49.00
Stemolecule™ Dorsomorphin , Cat. No. 04-0024 Dorsomorphin-2HCl is a potent inhibitor of AMP-activated protein kinase (AMPK) and bone morphogenic protein (BMP) signaling, functioning through inhibition of BMP type I receptors ALK2, ALK3 and ALK6 and thus blocks BMP-mediated SMAD1/5/8 phosphorylation.	2 mg $109.00
Stemolecule™ Dexamethasone , Cat. No. 04-0023 Stemolecule™ Dexamethasone is a glucocorticoid receptor agonist known to affect inflammatory responses, cellular proliferation, and differentiation in target tissues.	100 mg $49.00
Stemolecule™ Cyclopamine , Cat. No. 04-0022 Stemolecule™ Cyclopamine has been identified as a specific inhibitor of hedgehog singaling by direct binding to the heptahelical bundle of Smoothened. Hedgehog signaling is involved in embryogenesis as well as cancer progression. Cyclopamine has been utilized as a small molecule inducer of stem cell differentiation towards definitive endoderm pancreatic islet cells, as a modulator of cell proliferation, and as an anticancer drug.	2 mg $159.00
Stemolecule™ BI-D1870 , Cat. No. 04-0051 Stemolecule™ BI-D1870 is an inhibitor of Ribosomal S6 Kinase (RSK1, RSK2, RSK3 and RSK4 isoforms). BI-D1870 does not inhibit a large number of other kinases. Since BI-D1870 inhibits a potential positive effector of cell growth and survival, Stemolecule™ BI-D1870 may be useful in studies in these areas.	2 mg $549.00
Stemolecule™ Cyclic Pifithrin-α , Cat. No. 04-0040 Stemolecule™ Cyclic Pifithrin-α (Cyclic PFT-α) is a transcriptional inhibitor of p53. The reduction of p53 activity has been shown to enhance reprogramming efficiency of human and mouse somatic cells. Cyclic PFT-α sensitizes tumor cells to antimicrotubule agent induced apoptosis.	5 mg $109.00
Stemolecule™ Rock I Inhibitor , Cat. No. 04-0029 Rock inhibitors, including Stemolecule™ Rock I Inhibitor, have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency.	2 mg $239.00
Stemolecule™ Rock II Inhibitor , Cat. No. 04-0030 Stemolecule^TM Rock II Inhibitor is a specific inhibitor for type 2 Rho-associated, coiled-coil containing protein kinase (Rock). Rock inhibitors have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency.	2 mg $239.00
Stemolecule™ A769662 , Cat. No. 04-0052 Stemolecule™ A769662, a thienopyridone, was identified as an effective AMPK activator by screening a chemical library of over 700,000 compounds. The activation of AMPK inhibits mTOR (mammalian target of rapamycin) signaling, which is a positive affector of cell growth, proliferation and survival. Stemolecule™ A769662, therefore, may be useful as an inhibitor for both cell survival and cell proliferation.	10 mg $139.00
Stemolecule™ SHH Antagonist , Cat. No. 04-0032 Stemolecule^TM SHH Antagonist is an inhibitor of Sonic hedgehog signaling (SHH). Hedgehog signaling is involved in embryogenesis as well as cancer progression. The mechanism for this antagonist is unknown.	2 mg $239.00
Stemolecule™ Wnt Inhibitor IWP-4 , Cat. No. 04-0036 Stemolecule™ Wnt Inhibitor IWP-4 is an antagonist of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-4 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity¹. It blocks phosporylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.	2 mg $99.00
Stemolecule™ (-)-Indolactam V , Cat. No. 04-0020 Stemolecule™ (-)-Indolactam V is a PKC isozyme inhibitor identified in a high-content chemical screen as a small molecule inducer of human embryonic stem cell differentiation to functional insulin-secreting beta cells at the definitive endoderm cell stage.	300 μg $109.00
Stemolecule™ SMO Antagonist , Cat. No. 04-0031 Stemolecule™ SMO Antagonist is an analog of SANT-2, an inhibitor of Sonic hedgehog signaling. Hedgehog signaling is involved in embryogenesis as well as cancer progression. The mechanism of action of SMO Antagonist is allosteric inhibition of Smoothened (SMO), an integral membrane protein mediator of Hedgehog signaling.	2 mg $239.00
Stemolecule™ Wnt Inhibitor IWP-3 , Cat. No. 04-0035 Stemolecule™ Wnt Inhibitor IWP-3 is an antagonist of the Wnt/β-catenin pathway. Wnt Inhibitor IWP-3 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity¹. It blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin.	2 mg $99.00
Stemolecule™ All-Trans Retinoic Acid , Cat. No. 04-0021 Stemolecule™ All-Trans Retinoic Acid functions as a signaling molecule for various developmental pathways that control differentiation and proliferation. It has been used in various differentiation protocols, including B-cells, T cells and neurons, and implicated in specification of the embryonic anterior/posterior axis through Hox gene regulation.	100 mg $89.00
Stemolecule™ Wnt Inhibitor IWP-2 , Cat. No. 04-0034 Stemolecule™ Wnt Inhibitor IWP-2 is an antagonist of the Wnt/β-catenin pathway¹. Wnt Inhibitor IWP-2 prevents palmitylation of Wnt proteins by Porcupine (Porcn), a membrane-bound O-acyltransferase, thereby blocking Wnt secretion and activity¹. It blocks phosphorylation of the Lrp6 receptor and accumulation of both Dvl2 and β-catenin¹.	2 mg $99.00
Stemolecule™ Thiazovivin , Cat. No. 04-0017 Stemolecule™ Thiazovivin dramatically improves the survival of hESCs upon trypsinization¹. Thiazovivin in combination with inhibitors of the TGFβ receptor and the MEK pathway improve reprogramming efficiency more than 200-fold¹.	1 mg $259.00
Stemolecule™ BMP Inhibitor LDN-193189 , Cat. No. 04-0019 Stemolecule^TM BMP Inhibitor LDN-193189 functions primarily through inhibition of BMP type I receptors ALK2 and ALK3. LDN-193189 only weakly inhibits ALK4, ALK5, and ALK7. BMP signaling coordinates developmental patterning and has essential physiological roles in mature organisms.	2 mg $239.00
Components
Stemolecule™ Sodium Butyrate , Cat. No. 04-0005 In cultured mouse and human cells, sodium butyrate has been shown to inhibit both the mRNA and protein content of cyclin D1.¹ Sodium butyrate is a known inhibitor of histone deacetylases.²	500 mg $49.00
Stemolecule™ A83-01 , Cat. No. 04-0014 A83-01 is a potent small molecule that selectively inhibits ALK4, ALK5, and ALK7 receptors. This small molecule has been used to generate rat and human iPS cells towards a mouse ES cell like self-renewal state.	2 mg $119.00
Stemolecule™ ALK5 Inhibitor , Cat. No. 04-0015 ALK5 Inhibitor is a potent small molecule that selectively inhibits the TGF-β signaling pathway.	1 mg $99.00
Stemolecule™ BIO , Cat. No. 04-0003 BIO is the first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells.¹	2 mg $99.00
Stemolecule™ CHIR99021 , Cat. No. 04-0004 CHIR99021 is the most selective inhibitor of GSK3β.	2 mg $239.00
Stemolecule™ SB431542 , Cat. No. 04-0010 SB431542 has been shown to stimulate proliferation, differentiation, and sheet formation of endothelial cells derived from embryonic stem cells via ALK receptor inhibition.^1,2	5 mg $99.00
Stemolecule™ Purmorphamine , Cat. No. 04-0009 Stemolecule™ Purmorphamine promotes the differentiation of human and murine mesenchymal progenitor cells into osteoblasts.^1,2 It is ideal for stem cell and cell signaling researchers using human embryonic stem cells to investigate differentiation with small molecules.	5 mg $99.00
Stemolecule™ DAPT , Cat. No. 04-0041 DAPT may be useful in modulating Notch activity in embryonic stem cell differentiation studies. DAPT may be useful in studies evaluating potential treatments for Alzheimer's disease.	5 mg $139.00
Kits / Sets
Stemolecule™ TGF-beta Signaling Pathway Modulator Set , Cat. No. 00-0038 The Stemolecule™ TGF-β Small Molecule Set is an inclusive set of small molecules for regulating the transforming growth factor beta (TGF -β) signaling pathway. The set consists of three Stemolecules™, SB431542, A83-01, and ALK5 Inhibitor: activin receptor-like kinase (ALK) receptors that work as TGF-β. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.	3 compounds $239.00
Stemolecule™ Epigenetic Modifier Set , Cat. No. 00-0039 The Stemolecule™ Epigenetic Modifier Set is a complete set of small molecules for modulating epigenetic effects of DNA and histones. The set consists of four cell-permeable small molecules: BIX01294, Sodium Butryate, RG108, and Valproic Acid (VPA). BIX01294 is a selective inhibitor of G9a HMTase, Sodium Butryate is an inhibitor of histone deacetylases, RG108 is a DNA methyltransferase inhibitor, and VPA is an inhibitor of histone deacetylases. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.	4 compounds $259.00
Stemolecule™ iPS Cell Enhancer Set , Cat. No. 00-0040 The Stemolecule™ iPS Cell Generation Enhancer Set is a proven set of small molecules designed to improve iPS cell generation efficiency. The set consists of four cell-permeable small molecules: RG108, BIX1294, Valproic Acid (VPA), and R(+)Bay K 8644.	4 compounds $339.00
Stemolecule™ ROCK Signaling and Survival Pathway Set , Cat. No. 00-0057 The Stemolecule™ ROCK Signaling and Survival Pathway Set is a proven set of small molecules designed to enhance survival and cloning efficiency. The set consists of four cell-permeable small molecules: Y27632, Thiazovivin, Rock I Inhibitor and Rock II Inhibitor. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.	4 Compounds $699.00
Stemolecule™ SHH Signaling Pathway Modulator Set , Cat. No. 00-0058 The Stemolecule™ SHH Signaling Pathway Modulator Set contains five small molecules that affect the Sonic Hedgehog Signaling pathway. Purmorphamine is a Smoothened (SMO) receptor agonist. Cyclopamine is a heptahelical bundle of SMO inhibitor. Both KAAD-Cyclopamine and Smo Antagonist inhibit SMO. SHH Antagonist is an antagonist for the pathway.	5 Compounds $789.00
Stemolecule™ MAPK Signaling Pathway Modulator Set , Cat. No. 00-0041 The Stemolecule™ MAPK Signaling Pathway Modulator Set consists of three cell-permeable small molecules: PD0325901, PD173074, and SC1 (Pluripotin), which can modulate the MAPK signaling cascade. PD0325901 is a MEK inhibitor; PD173074 is an ATP-competitive inhibitor of the FGF receptor, known to activate the MAPK/ERK cascade; and SC1 (Pluripotin) acts through dual inhibition of ERK 1 and Ras-GAP. Each small molecule is tested for purity, accurate mass and structure, and toxicity in mouse embryonic stem cells.	3 compounds $359.00
iPSC Generation
Stemolecule™ Tranylcypromine hydrochloride , Cat. No. 04-0033 Stemolecule™ Tranylcypromine inhibits BHC110/LSD1, a histone H3 lysine 4 demethylation enzyme with close homology to monoamine oxidases. Treatment of P19 embryonal carcinoma cells with tranylcypromine resulted in global increase in H3K4 methylation as well as transcriptional derepression of the pluripotent stem cell marker Oct4.	10 mg $49.00
iPSC Generation Components
Stemolecule™ BIX01294 , Cat. No. 04-0002 BIX01294 enhances reprogramming efficiency of neural progenitor cells to the same levels as when four transcription factors (Oct4, Klf4, Sox2 and c-Myc) were introduced to somatic cells.^1,2	5 mg $99.00
Stemolecule™ Y27632 , Cat. No. 04-0012 Y27632 is a Rho-associated kinase ROCK inhibitor that enhances survival and cloning efficiency of human embryonic stem cells.	2 mg $139.00
Stemolecule™ Valproic Acid , Cat. No. 04-0007 VPA has been shown to enhance iPS generation in a three-factor transduction (Oct4, Klf4 and Sox2) without introduction of the c-Myc oncogene.¹	5 g $49.00
Stemolecule™ SC1 (Pluripotin) , Cat. No. 04-0011 SC1 (Pluripotin) is a high-quality, affordable small molecule LIF replacement for mouse embryonic (mES) cell self-renewal. SC1 maintains mES cells in an undifferentiated self-renewal state in the absence of LIF, feeder cells, or serum.	1 mg $99.00
Stemolecule™ PD0325901 , Cat. No. 04-0006 PD0325901 selectively binds and inhibits MEK, which may result in the inhibition of the phosphorelation and activation of MAPK/ERK.^1,2	2 mg $239.00
Stemolecule™ R(+)Bay K 8644 , Cat. No. 04-0013 R(+)Bay K 8644 is a small molecule that enhances reprogramming efficiency when used with BIX01294.	5 mg $149.00
Stemolecule™ PD173074 , Cat. No. 04-0008 PD173074 inhibits the FGF signaling pathway.	2 mg $119.00
Stemolecule™ RG108 , Cat. No. 04-0001 Stemolecule™ RG108 is the highest purity preparation available, only from Stemgent. RG108 is a cell-permeable, specific DNA methyltransferase inhibitor that displays anti-proliferative properties with no detectable cytotoxic effects.¹	10 mg $129.00
Pathways Kits / Sets
Stemolecule™ Wnt Signaling Pathway Set , Cat. No. 00-0059 The Stemolecule™ Wnt Signaling Pathway Modulator Set contains five cell permeable, small molecules known to inhibit the Wnt/β-catenin signaling pathway. Both BIO and CHIR99021 inhibit glycogen synthase kinase 3β (GSK3β). IWP-2, IWP-3, and IWP-4 prevent palmitylation of Wnt proteins by porcupine (Porcn), a membrane-bound O-acyltransferase.	5 Compounds $509.00
Matrices
Components
Stemgent® Mouse Laminin , Cat. No. 06-0002 Stemgent™ Mouse Laminin is 2X more active than RBM products, 98% pure, pathogen- and endotoxin-free, validated on ES and iPS cells, and provides more defined conditions, making it a superior cell attachment matrix for maintaining the undifferentiated state.	1 mg (1 mg/ml) $99.00
Cell Lines
iPSC Generation
Stemgent® Human Foreskin Fibroblasts BJ , Cat. No. 08-0026 The Stemgent® Human Foreskin Fibroblast Cells - BJ are high-quality, contamination-free cells that have been proven to reprogram to produce induced pluripotent stem (iPS) cells in the labs at Stemgent. They can be used for studying reprogramming mechnanisms, generating iPS cells, or for use as a reprogramming control alongside a specific cell type.	1x 10⁶ cells per vial $399.00
iPSC Generation Components
Stemgent® Mouse Primary iPS Cells-NNeo , Cat. No. 08-0012 The Stemgent™ Mouse Primary iPS Cells-NNeo harbor the reverse tetracycline transactivator (rtTA) targeted to the ROSA26locus (ROSA26-M2rtTA), Oct4 cDNA under the control of tetracycline operator targeted to the type I collagen locus, a neomycin (neo) resistance gene in the endogenous Nanog locus, and the Dox-inducible transcription factors Klf4, Sox2 and c-Myc inserted during lentivirus transduction. Injection of these cells into blastocysts results in the generation of chimeric mice from which a variety of cells can be isolated for secondary reprogramming studies.	2 x 10^5 cells/vial $499.00
Stemgent® Mouse Primary iPS Cells-WP5 , Cat. No. 08-0007 Stemgent™ Mouse Primary iPS Cells-WP5 were created by transducing genetically unmodified mouse embryonic fibroblasts with murine retroviruses individually encoding the four transcription factors (Oct4, Sox2, Klf4, and c-Myc) that have been shown to induce the reprogramming of adult somatic cells to a pluripotent state. Injection of Stemgent™ Mouse Primary iPS Cells-WP5 into blastocysts resulted in the generation of chimeric mice.	2 x 10^5 cells/vial $499.00
Stemgent® Mouse Primary iPS Cells-T1b , Cat. No. 08-0006 Stemgent™ Mouse Primary iPS Cells-T1b were created by transducing genetically unmodified mouse tail tip fibroblasts with murine retroviruses individually encoding the four transcription factors (Oct4, Sox2, Klf4, and c-Myc) that have been shown to induce the reprogramming of adult somatic cells to a pluripotent state. They are ideal for use as a control alongside reprogramming studies or studying epigenetic modifications.	2 x 10^5 cells/vial $499.00
Antibodies / Biomarkers
Stemgent^® Rat anti-Mouse OC2-1C6 Antibody , Cat. No. 09-0057 The Stemgent^® Rat anti-Mouse OC2-1C6 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Mouse anti-Human HPi4 Antibody , Cat. No. 09-0051 The Stemgent^® Mouse anti-Human HPi4 Antibody, clone HIC1-5F10, detects pancreas endocrine (islet) cells. This clone is one of the first antibodies described for pancreatic endocrine cell types and has been shown to allow identification and isolation of human pancreatic cell sub-populations. This antibody is specific for multiple endocrine types, including, but not limited to, insulin-expressing beta cells. The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections¹. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreatic development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent® Mouse anti-Human HPd2 Antibody , Cat. No. 09-0047 Stemgent^® Mouse anti-Human HPd2, (Human Pancreas and Liver Duct Antibody), clone DHIC3-5H10, is a novel monoclonal antibody that reacts with a cell surface molecule on human pancreatic and liver duct cells.	50 µg (100µl at 0.5mg/ml) $189.00
Stemgent^® Mouse anti-Human HPx2 Antibody , Cat. No. 09-0053 The Stemgent^® Mouse anti-Human HPx2 Antibody, clone HIC1-1C10, detects pancreatic exocrine cells. This clone is one of the first antibodies described for pancreatic exocrine cells and has been shown to be useful in identification and isolation of human pancreatic cell sub-populations. The HPx2 antigen has been shown to be co-expressed with amylase (marker for acinar cells). The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent® Mouse anti-Human HPd1 Antibody , Cat. No. 09-0046 Stemgent® Mouse anti-Human HPd1, (Human Pancreas and Liver Duct Antibody), clone DHIC2-4A10, is a novel monoclonal antibody that reacts with a cell surface molecule on human pancreatic and liver duct cells.	50 µg (100µl at 0.5mg/ml) $189.00
Stemgent® Mouse anti-Human HPα1 Antibody , Cat. No. 09-0054 The Stemgent® Mouse anti-Human HPα1 Antibody, clone DHIC2-2B4, detects pancreatic alpha cells. This clone is newly-described specificity for pancreatic subpopulations and has been shown to be useful in identification and isolation of human pancreatic cell types. This antibody has been reported to detect an islet cell subpopulation distinct from beta cells¹. The clone has been characterized by flow cytometry and immunohistochemistry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Mouse anti-Human HPα2 Antibody , Cat. No. 09-0055 The Stemgent^® Mouse anti-Human HPa2 Antibody, clone DHIC2-2B4, detects pancreatic alpha cells. This clone is one of the first antibodies described for pancreatic subpopulations and has been shown to be useful in identification and isolation of human pancreatic cell types. This antibody has been reported to detect an islet cell subpopulation distinct from beta cells when tested on human pancreas frozen sections. The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Mouse anti-Human HPi2 Antibody , Cat. No. 09-0049 The Stemgent^® Mouse anti-Human HPi2 Antibody, clone HIC1-2B4, detects pancreas endocrine (islet) cells. This clone is one of the first antibodies described for pancreatic endocrine cells and has been shown to be useful in identification and isolation of human pancreatic cell sub-populations. This antibody is specific for multiple endocrine types, including, but not limited to, insulin-expressing beta cells. The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® StainAlive™ DyLight™ 488 Mouse anti-Human TRA-1-60 Antibody , Cat. No. 09-0068 Stemgent® StainAlive™ DyLight™488 antibodies enable direct staining of live mouse and human ES and iPS cells, eliminating the fix step and exposure to harsh chemicals that leave cells damaged or destroyed. StainAlive™ antibodies preserve precious stem cells after staining for direct visualization of the reprogramming process and downstream experimentation.	50 µg (100ul at 0.5 mg/ml) $250.00
Stemgent® Human ES/iPS Cell Characterization Set , Cat. No. 00-0017 The Stemgent™ Human ES/iPS Cell Characterization Set is a specific, sensitive, affordable, all-in-one stem cell-verified set of tools designed for researchers needing to monitor pluripotency by analyzing the undifferentiated and differentiated status of human embryonic stem (ES) and induced pluripotent stem (iPS) cells by detecting alkaline phosphatase activity and the four pluripotentency biomarkers SSEA-4, TRA-1-60, Oct4, and Nanog. Stemgent has screened these antibodies on human ES cells using ICC and flow cytometry, and selected them as the best antibody set for researchers needing to demonstrate pluripotency of human ES cells.	50 assays $699.00
Stemgent^® Mouse anti-Human HPi1 Antibody , Cat. No. 09-0048 The Stemgent^® Mouse anti-Human HPi1 Antibody, clone HIC0-4F9, detects pancreas endocrine (islet) cells. This clone is one of the first antibodies described for pancreatic endocrine cells and has been shown to allow identification and isolation of human pancreatic cell sub-populations. This antibody is specific for multiple endocrine types, including, but not limited to, insulin-expressing beta cells. The clone has been characterized by flow cytometry and by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse MIC1-1C3 Antibody , Cat. No. 09-0056 The Stemgent^® Rat anti-Mouse MIC1-1C3 Antibody detects mouse liver duct and pancreas cells. This clone was raised against mouse islet cells. The clone was characterized by flow cytometry and IHC, and each antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Mouse anti-Human HPi3 Antibody , Cat. No. 09-0050 The Stemgent^® Mouse anti-Human HPi3 Antibody, clone HIC1-7H10, detects pancreas endocrine (islet) cells. This clone is one of the first antibodies described for pancreatic endocrine cells and has been shown to allow identification and isolation of human pancreatic cell sub-populations. This antibody is specific for multiple endocrine types, including, but not limited to, insulin-expressing beta cells. The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreas development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-1D11 Antibody , Cat. No. 09-0058 The Stemgent^® Rat anti-Mouse OC2-1D11 Antibody detects mouse liver duct cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-2A6 Antibody , Cat. No. 09-0059 The Stemgent^® Rat anti-Mouse OC2-2A6 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and by IHC; and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-2F3 Antibody , Cat. No. 09-0060 The Stemgent^® Rat anti-Mouse OC2-2F3 Antibody detects mouse liver duct cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-3C7 Antibody , Cat. No. 09-0062 The Stemgent^® Rat anti-Mouse OC2-3C7 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-4E8 Antibody , Cat. No. 09-0063 The Stemgent^® Rat anti-Mouse OC2-4E8 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent^® Rat anti-Mouse OC2-6E10 Antibody , Cat. No. 09-0064 The Stemgent^® Rat anti-Mouse OC2-6E10 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and IHC, and every antibody preparation is tested on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent® DyLight™ 549 Mouse anti-Human Tra-1-81 Antibody , Cat. No. 09-0082 Stemgent® DyLight™ 549 Mouse anti-Human TRA-1-81 Antibody was screened on mouse and human embryonic stem (ES) cells using immunocytochemistry (ICC) and was selected as the best conjugated TRA-1-81 antibody available for visualization of EC/ES/iPS cells. This antibody can be useful for direct visualization of the reprogramming process to iPS colonies.	50 μg (100μl at 0.5 mg/ml) $250.00
Stemgent® DyLight™ 488 Mouse anti-Mouse/Human SSEA-1 Antibody , Cat. No. 09-0070 The MC-480 monoclonal antibody reacts with mouse and human stage-specific embryonic antigen-1 (SSEA-1). It is expressed on murine embryonal carcinoma cells, murine embryonic stem cells, and murine and human germ cells. It is widely used as a positive surface marker for mouse undifferentiated stem cells and a negative surface marker for human undifferentiated stem cells.	50 μg (100 μl at 0.5 mg/ml) $199.00
Stemgent® Purified Mouse anti-Human Nestin Antibody , Cat. No. 09-0045 Stemgent® Purified Mouse anti-Human Nestin Antibody was screened on a human neural progenitor cell line using immunocytochemistry (ICC) and flow cytometry (FC), and selected, among those tested, as the best application-verified monoclonal anti-Nestin antibody for stem cell research applications.	50 µg; 0.1 ml (0.5 mg/ml) $299.00
Stemgent® Rabbit anti-Human Vimentin Antibody , Cat. No. 09-0077 Vimentin is a marker for cells of mesenchymal origin. Vimentin is the most ubiquitous intermediate filament (IF) protein, and is found in many kinds of mesenchymal and epithelial cells, including leukocytes, blood vessel endothelial cells, and developing neuronal and astrocytic precursor cells. Vimentin is the first IF protein to be expressed in development. Vimentin is present in many different tumor types but is particularly expressed in those originated from mesenchymal cells. The Stemgent® Rabbit anti-Human Vimentin Antibody is a rabbit monoclonal antibody screened by Stemgent and selected as the best reagent available for visualization of vimentin-expressing cells. It has been tested by immunocytochemistry, and it has been reported to detect vimentin in immunohistochemistry, Western blot and flow cytometry applications. It detects vimentin from multiple species.	100 µl (See Recommended Usage section for additional information) $249.00
Stemgent® Rat anti-Mouse OC2-3C5 Antibody , Cat. No. 09-0061 The Stemgent® Rat anti-Mouse OC2-3C5 Antibody detects mouse liver periductal cells. This clone is raised against mouse liver cells undergoing oval cell activation. The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. This antibody has been identified as a useful tool for identification and isolation of liver cell progenitors in mouse models of hepatic cell development¹.	50 µg (100 µl at 0.5 mg/ml) $189.00
Stemgent® StainAlive™ DyLight™ 488 Mouse anti-Human TRA-1-81 Antibody , Cat. No. 09-0069 Stemgent® StainAlive™ DyLight™488 antibodies enable direct staining of live mouse and human ES and iPS cells, eliminating the fix step and exposure to harsh chemicals that leave cells damaged or destroyed. StainAlive™ antibodies preserve precious stem cells after staining for direct visualization of the reprogramming process and downstream experimentation.	50 µg (100 µl at 0.5 mg/ml) $250.00
Stemgent® StainAlive™ DyLight™ 488 Mouse anti-SSEA-1 Antibody , Cat. No. 09-0067 Stemgent® StainAlive™ DyLight™488 antibodies enable direct staining of live mouse and human ES and iPS cells, eliminating the fix step and exposure to harsh chemicals that leave cells damaged or destroyed. StainAlive™ antibodies preserve precious stem cells after staining for direct visualization of the reprogramming process and downstream experimentation.	50 µg (100 µl at 0.5 mg/ml) $250.00
Stemgent® Purified Rabbit anti-Mouse/Human Pax6 Antibody , Cat. No. 09-0075 The Stemgent® Purified Rabbit anti-Mouse/Human Pax6 Antibody was screened the neuroanl cells differentiated from the mouse and human ES cells by immunocytochemistry and selected as the best application-tested antibody for the Pax-6 molecule. Pax-6 is a nuclear transcription factor expressed in the brain and developing nervous system, endocrine system and eyes and is essential for the development of brain, the eyes, nose, nervous system and endocrine glands. This antibody was generated against a C-terminal peptide of the mouse Pax-6 protein. The sequence is highly conserved among Pax-6 of various species. The Stemgent® Purified Rabbit anti-Mouse/Human Pax6 Antibody can be used in the study of brain, neuronal and olfactory development.	50 µg (100 µl at 0.5 mg/ml) $259.00
Stemgent® Purified Mouse anti-Mouse/Human βIII Tubulin Antibody , Cat. No. 09-0076 The Stemgent® Purified Mouse anti-Mouse/Human βIII-Tubulin Antibody was screened on mouse and human ES cells by immunocytochemistry (ICC) and selected as the best application-tested antibody for βIII-tubulin. The βIII-tubulin form is predominately expressed in cells of neuronal origin and it is one of the earliest molecules expressed during neuronal differentiation. βIII-tubulin is thought to be one of the earliest markers to signal neuronal commitment in primitive neuroepithelium. This antibody was generated against amino acids 441-448, derived from the C-terminus of the human βIII-tubulin protein.	50 µg (0.5 mg/ml) $209.00
Stemgent^® Mouse anti-Human HPx1 Antibody , Cat. No. 09-0052 The Stemgent^® Mouse anti-Human HPx1 Antibody, clone HIC0-3B3, detects pancreatic exocrine cells. This clone is one of the first antibodies described for pancreatic exocrine cells and has been shown to be useful in identification and isolation of human pancreatic cell sub-populations. The HPx1 antigen has been shown to be co-expressed with amylase (marker for acinar cells). The clone has been characterized by flow cytometry and each preparation is tested by IHC on acetone-fixed frozen sections. With this antibody investigators in stem cell, diabetes and transplantation research will be able to purify and characterize various lineages in pancreatic development.	50 µg (100 µl at 0.5 mg/ml) $189.00
Kits / Sets
Stemgent® Alkaline Phosphatase Staining Kit II , Cat. No. 00-0055 The Stemgent® Alkaline Phosphatase Staining Kit II provides a convenient protocol and stable reagents for the phenotypic assessment of the undifferentiated state of ES and iPS cells. The AP Kit II extends the usability window of the mixed staining solutions from five to 30 minutes and allows fixation for up to two minutes for hassle-free detection of AP activity.	50 tests $79.00
Stemgent® Alkaline Phosphatase Staining Kit , Cat. No. 00-0009 The Stemgent™ Alkaline Phosphatase Staining Kit is a specific and sensitive tool for phenotypic assessment of ES cell differentiation or iPS cell generation from somatic cells.	50 assays $69.00
Stemgent® Human MSC Characterization Set , Cat. No. 00-0020 The Stemgent® Human MSC Characterization Set is a specific and sensitive application-tested tool designed to characterize and/or isolate mesenchymal stem cells (MSCs) derived from human bone marrow and other sources. The five Stemgent® antibodies included in this characterization set have been verified by their performance in immunocytochemistry (ICC) and flow cytometry (FC) applications on normal human MSCs to ensure the highest quality results.	50 assays $499.00
Stemgent® Mouse ES/iPS Cell Characterization Set , Cat. No. 00-0016 The Stemgent™ Mouse ES/iPS Cell Characterization Set is a specific, sensitive, affordable, all-in-one stem cell-verified set of tools designed for researchers needing to monitor pluripotency by analyzing the undifferentiated and differentiated status of mouse embryonic stem (ES) and induced pluripotent stem (iPS) cells by detecting alkaline phosphatase activity and the three pluripotent biomarkers SSEA-1, Oct4, and Nanog.	50 assays $599.00
Stemgent® Pluripotency Characterization Set , Cat. No. 00-0013 The Stemgent® Pluripotency Characterization Set is a specific and sensitive, stem cell-tested tool designed for analyzing the undifferentiation/differentiation status of embryonic stem (ES)/ induced pluripotent stem (iPS) cells by measuring their alkaline phosphatase (AP) activity, cell-surface stage-specific antigens (SSEA-1, SSEA-3, and SSEA-4), as well as expression of TRA-1-60 and TRA-1-81 antigens.	50 assays $559.00
Secondary
Stemgent® Cy™ 3 Goat anti-Rabbit IgG Antibody , Cat. No. 09-0037 Stemgent® Cy™ 3 Goat anti-Rabbit IgG Antibody was screened on mouse and/or human embryonic stem (ES) cells using immunocytochemistry (ICC) and selected as the best application-verified secondary antibody for stem cell research applications.	100 µg $69.00
Stemgent® Cy™ 3 Goat anti-Rat IgG + IgM Antibody , Cat. No. 09-0038 Stemgent® Cy™ 3 Goat anti-Rat IgG + IgM Antibody was screened on human stem cells using immunocytochemistry (ICC) and selected as the best application-tested secondary antibody, among those tested, for stem cell research applications.	100 μg (0.5 mg/ml) $89.00
Stemgent® Cy™ 3 Goat anti-Mouse IgG + IgM Antibody , Cat. No. 09-0036 Stemgent® Cy™ 3 Goat anti-Mouse IgG + IgM Antibody was screened on mouse embryonic stem (ES) cells using immunocytochemistry (ICC) and selected as the best application-verified secondary antibody for stem cell research applications.	100 µg; 0.2ml (0.5 mg/ml) $89.00
Stemgent® DyLight™ 488 Goat anti-Mouse IgG + IgM Antibody , Cat. No. 09-0033 Stemgent® DyLight™ 488 Goat anti-Mouse IgG + IgM Antibody was screened on mouse and/or human embryonic stem (ES) cells using immunocytochemistry (ICC) and flow cytometry (FC), and selected as the best application-verified secondary antibody for stem cell research applications.	100 µg (0.5 mg/ml) $89.00
Stemgent® DyLight™ 488 Goat anti-Rabbit IgG Antibody , Cat. No. 09-0034 Stemgent® DyLight™ 488 Goat anti-Rabbit IgG Antibody was screened on mouse and/or human stem cells using immunocytochemistry (ICC) and flow cytometry (FC), and selected as the best application-verified secondary antibody for stem cell research applications.	100 μg $89.00
Stemgent® DyLight™ 488 Goat anti-Rat IgG + IgM Antibody , Cat. No. 09-0035 Stemgent® DyLight™ 488 Goat anti-Rat IgG + IgM Antibody was screened on human embryonic stem (ES) cells using immunocytochemistry (ICC) and flow cytometry (FC), and selected as the best application-tested secondary antibody, among those screened, for stem cell research applications.	100 μg; 0.2 ml (0.5 mg/ml) $89.00
Stemgent® HRP Goat anti-Mouse IgG Antibody , Cat. No. 09-0039 Stemgent® HRP Goat anti-Mouse IgG Antibody was screened on human embryonic stem (ES) cells by western blot analysis and selected as the best application-tested secondary antibody, among those tested, for stem cell research applications.	100 μg; 0.5ml (0.2 mg/ml) $119.00
Stemgent® HRP Goat anti-Rat IgG (light chain) Polyclonal Antibody , Cat. No. 09-0040 Stemgent® HRP Goat anti-Rat IgG (light chain) Polyclonal Antibody was screened on embryonic stem (ES) cells by western blot analysis and selected as the best application-tested secondary antibody, among those tested, for stem cell research applications.	100 µg, 0.5 ml (0.2 mg/ml) $119.00
Stemgent® HRP Mouse anti-Rabbit IgG Antibody , Cat. No. 09-0041 Stemgent® HRP Mouse anti-Rabbit IgG Antibody was screened on human embryonic stem (ES) cells by western blot analysis and selected as the best application-tested secondary antibody, among those tested, for stem cell research applications.	100 μg; 0.5ml (0.2 mg/ml) $119.00
Pluripotency
Stemgent® Dylight™488 Rabbit anti-Human/Mouse Oct4 Antibody , Cat. No. 09-0071 Stemgent® DyLight™ 488 Rabbit anti-Human/Mouse Oct4 Antibody was screened on human and mouse ES cells using ICC and flow cytometry and selected as the best Oct4 antibody available for researchers needing to demonstrate pluripotency.	50 µg (116 µl at 0.43 mg/ml) $219.00
Stemgent® Mouse/Human ES/iPS Cell Nuclear Marker Set , Cat. No. 00-0022 The Stemgent™ Mouse/Human ES/iPS Cell Nuclear Marker Set is a specific, sensitive, affordable, all-in-one stem cell-verified set of tools designed for monitoring pluripotency of human or mouse embryonic stem (ES) and induced pluripotent stem (iPS) cells. The set includes the three Stemgent™ antibodies Nanog, Sox2, and Oct4 which have been verified in immunocytochemistry (ICC), flow cytometry (FC), or western blot (WB) applications on both human and mouse ES cells to ensure the highest quality antibodies.	50 assays $479.00
Stemgent® Phycoerythrin (PE) Rat anti-Human SSEA-3 Antibody , Cat. No. 09-0044 The Stemgent® Phycoerythrin (PE) Rat anti-Human SSEA-3 Antibody was screened on human embryonic stem (ES) cells using flow cytometry (FC) and selected as the best stem cell-verified PE conjugated anti-SSEA-3 antibody available for identifying, characterizing, and monitoring pluripotency of human ES cells.	50 assays $149.00
iPSC Generation
Stemgent® Purified Mouse anti-Human c-Myc Antibody , Cat. No. 09-0032 Stemgent® Purified Mouse anti-Human c-Myc Antibody was screened on cells transfected with a human c-Myc construct by western blot analysis and selected as the best application-tested c-Myc antibody, among those tested, for stem cell research applications. c-Myc is one of the key transcription factors used to reprogram mouse and human fibroblasts to a pluripotent state.	100 µl (0.5 mg/ml) $139.00
Mesenchymal
Stemgent® Purified Mouse anti-Human CD105 Antibody , Cat. No. 09-0030 Stemgent® Purified Mouse anti-Human CD105 Antibody was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD105 antibody for characterizing and/or isolating human mesenchymal stem cells.	50 μg $149.00
Stemgent® Purified Mouse anti-Human CD166 Antibody , Cat. No. 09-0031 Stemgent® Purified Mouse anti-Human CD166 Antibody (ALCAM) was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD166 antibody for characterizing and/or isolating human mesenchymal stem cells. Stemgent® Purified Mouse anti-Human CD166 Antibody (ALCAM) was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD166 antibody for characterizing and/or isolating human mesenchymal stem cells.	50 μg $99.00
Stemgent® Purified Mouse Anti-Human CD29 Antibody , Cat. No. 09-0025 Stemgent™ Purified Mouse anti-Human CD29 Antibody was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD29 antibody for characterizing and/or isolating human mesenchymal stem cells.	50 μg $99.00
Stemgent® Purified Mouse anti-Human CD34 Antibody , Cat. No. 09-0026 Stemgent® Purified Mouse anti-Human CD34 Antibody was screened on normal human mesenchymal stem cells (MSCs) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD34 negative selection antibody for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources.	50 μg $99.00
Stemgent® Purified Mouse anti-Human CD45 Antibody , Cat. No. 09-0028 Stemgent® Purified Mouse anti-Human CD45 Antibody was screened on normal human mesenchymal stem cells (MSCs) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD45 negative selection antibody for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources.	50 μg $99.00
Stemgent® Purified Mouse anti-Human CD90 Antibody , Cat. No. 09-0029 Stemgent® Purified Mouse anti-Human CD90 Antibody was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD90 antibody for characterizing and/or isolating human mesenchymal stem cells.	50 μg $129.00
Stemgent® Purified Rat anti-Mouse/Human CD44 Antibody , Cat. No. 09-0027 Stemgent™ Purified Rat anti-Mouse/Human CD44 antibody was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD44 antibody available for characterizing and/or isolating human mesenchymal stem cells.	50 μg $99.00
Isotype Contols
Stemgent® StainAlive™ DyLight™ 488 Mouse IgM, κ Isotype Control Antibody , Cat. No. 09-0072 Stemgent® StainAlive™ Dylight™ 488 Mouse IgM, κ Isotype Control is the negative control antibody for use with the StainAlive™ collection of antibodies. Stemgent® StainAlive™ DyLight™ 488 Antibodies are novel stem cell-verified antibodies available for direct staining of live mouse and human ES and iPS cells, minimizing fragile stem cell exposure to harsh chemicals, providing a method for preserving live stem cells after staining for downstream experimentation, and for direct visualization of the reprogramming process without using a fix step that can leave cells damaged or destroyed.	50 µg (0.1 ml at 0.5 mg/ml) $100.00
Isotype Contols Components
Stemgent^® Affinity Purified Mouse IgG3, κ Isotype Control Antibody , Cat. No. 09-0008 The mouse IgG3, κ, was chosen as an isotype control immunoglobulin after screening with a variety of resting, activated, live, and fixed mouse, rat, and human tissues.	50 μg $49.00
Stemgent^® Phycoerythrin (PE) Rat IgM, κ Isotype Control Antibody , Cat. No. 09-0013 The monoclonal rat IgM, κ is used as an isotype control immunoglobulin.	1 ml $79.00
Stemgent^® Affinity Purified Mouse IgM, κ Isotype Control Antibody , Cat. No. 09-0007 The isotype of clone MM-30, mouse IgM, κ, was chosen as an isotype control after screening on a variety of resting, activated, live, and fixed mouse, rat and human tissues.	50 µg $49.00
Stemgent^® Affinity Purified Rat IgM, κ Isotype Control Antibody , Cat. No. 09-0015 Application tested Rat IgM, κ Isotype Control for ES cell surface marker SSEA-3	50 μg $49.00
Stemgent^® Phycoerythrin (PE) Mouse IgM Isotype Control Antibody , Cat. No. 09-0002 The isotype was used as a negative control to distinguish specific from non-specific binding of fluorochrome-conjugated mouse IgM antibodies.	1 ml $79.00
Stemgent^® Phycoerythrin (PE) Mouse IgG₃, κ Isotype Control Antibody , Cat. No. 09-0004 The mouse IgG₃, κ, was chosen as an isotype control immunoglobulin after screening with a variety of resting, activated, live, and fixed mouse, rat, and human tissues.	1 ml $79.00
iPSC Generation Components
Stemgent^® Affinity Purified anti-Human LIN28 Antibody , Cat. No. 09-0022 Affinity Purified anti-Human Lin28 was screened on HeLa cells using ICC and selected as the best Lin28 antibody available for researchers needing to detect Lin28 transgene expression.	100 μl $229.00
Stemgent® Purified Mouse anti-Mouse/Human Klf4 Antibody , Cat. No. 09-0021 Affinity Purified anti-Mouse/Human Klf4 was screened on NIH3T3 cells using ICC and selected as the best Klf4 antibody availalbe for researchers needing to detect Klf4 transgene expression.	100 μl $139.00
Pluripotency Components
Stemgent^® Affinity Purified anti-Human SSEA-4 Antibody , Cat. No. 09-0006 SSEA-4 antibody is widely used to characterize human embryonic stem (ES) cells and to monitor their differentiation, as the expression of SSEA-4 on human ES cells is down-regulated upon differentiation.	50 µg $169.00
Stemgent^® Affinity Purified anti-Human TRA-1-60 Antibody , Cat. No. 09-0010 The TRA-1-60 monoclonal antibody reacts with a pluripotent-stem-cell-specific antigen expressed on undifferentiated human embryonic stem (ES) cells, embyronal carcinoma (EC) cells, and embryonic germ (EG) cells.	50 μg $99.00
Stemgent^® Affinity Purified anti-Human TRA-1-81 Antibody , Cat. No. 09-0011 The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific antigen expressed upon the surface of human embryonic stem (ES) cells, embyronal carcinoma (EC) cells, and embryonic germ (EG) cells.	50 μg $99.00
Stemgent^® Affinity Purified anti-Mouse/Human Rex1 Antibody , Cat. No. 09-0019 Affinity Purified anti-Mouse/Human Rex1 was screened on human and mouse ES cells using ICC and flow cytometry and selected as the best Rex1 antibody available for researchers needing to demonstrate pluripotency.	100 μl $179.00
Stemgent^® Affinity Purified anti-Mouse/Human SSEA-1 Antibody , Cat. No. 09-0005 SSEA-1 is an antigenic epitope defined as a Lewis X carbohydrate structure. It is expressed on murine embryonal carcinoma cells, murine embryonic stem cells, and murine and human germ cells.	50 µg $169.00
Stemgent^® Affinity Purified anti-Human SSEA-3 Antibody , Cat. No. 09-0014 SSEA-3 can be used to characterize embryonic cells and monitor their differentiation. The expression of SSEA-3 on human ES cells is down-regulated upon differentiation.	50 μg $139.00
Stemgent^® Phycoerythrin (PE) anti-Human TRA-1-60 Antibody , Cat. No. 09-0009 The TRA-1-60 monoclonal antibody reacts with a pluripotent-stem-cell-specific antigen expressed on undifferentiated human embryonic stem (ES) cells, embyronal carcinoma (EC) cells, and embryonic germ (EG) cells.	1 ml $139.00
Stemgent^® Phycoerythrin (PE) anti-Mouse/Human SSEA-1 Antibody , Cat. No. 09-0001 SSEA-1 is an antigenic epitope defined as a Lewis X carbohydrate structure. It is expressed on murine embryonal carcinoma cells, murine embryonic stem cells, and murine and human germ cells.	1 ml $159.00
Stemgent^® Phycoerythrin (PE) anti-Human TRA-1-81 Antibody , Cat. No. 09-0012 The TRA-1-81 monoclonal antibody reacts with a pluripotent-stem-cell-specific antigen expressed upon the surface of human embryonic stem (ES) cells, embyronal carcinoma (EC) cells, and embryonic germ (EG) cells.	1 ml $139.00
Stemgent^® Phycoerythrin (PE) anti-Human SSEA-4 Antibody , Cat. No. 09-0003 SSEA-4 antibody is widely used to characterize human embryonic stem cells (ES) and to monitor their differentiation, as the expression of SSEA-4 on human ES cells is down-regulated upon differentiation.	1 ml $159.00
Pluripotency iPSC Generation
Stemgent® Purified anti-Mouse/Human Sox2 Antibody , Cat. No. 09-0024 Stemgent™ Purified Rabbit anti-Mouse/Human Sox2 Antibody was screened on human and mouse ES cells using ICC and flow cytometry and selected as the best Sox2 antibody available for researchers needing to demonstrate pluripotency.	100 μl $119.00
Pluripotency iPSC Generation Components
Stemgent^® Affinity Purified anti-Mouse/Human Nanog Antibody , Cat. No. 09-0020 Affinity Purified anti-Mouse/Human Nanog was screened on human and mouse ES cells using ICC and selected as the best Nanog antibody available for researchers needing to demonstrate pluripotency.	100 μl $259.00
Stemgent® Purified Rabbit anti-Mouse/Human Oct4 Antibody , Cat. No. 09-0023 Affinity Purified anti-Mouse/Human Oct4 was screened on human and mouse ES cells using ICC and flow cytometry and selected as the best Oct4 antibody available for researchers needing to demonstrate pluripotency.	100 μl $139.00
Cytokines
Stemfactor™ SHH (C24II) (Human Recombinant) , Cat. No. 03-0008 Stemfactor™ SHH (C24II) (Human Recombinant) is an affordable highly-purified cytokine produced from human cells to study differentiation and/or expansion of human and mouse embryonic and adult stem cells. Stemfactor™ SHH has high purity and low endotoxin levels and is tested for biological activity.	25 μg $249.00
Stemfactor™ Wnt-3a (Mouse Recombinant) , Cat. No. 03-0009 Stemfactor™ Wnt-3a (Mouse Recombinant) assists in regulation of cell fate and patterning during stem cell differentiation, has a proliferative effect in mouse embryonic stem (mES) cells, and is required for the generation of mesendodermal lineages. Wnt-3a is implicated in self renewal and expansion of the blood forming stem cell in the hematopoietic compartment. In neural stem cells, Wnt-3a regulates self renewal, expansion and survival.	10 µg $299.00
Stemfactor™ BMP-4 (Human Recombinant) , Cat. No. 03-0007 Stemfactor™ BMP-4, Human Recombinant was stringently tested for bioactivity, low endotoxin levels, high purity, and structural homogeneity, and is ideal for studying differentiation in hES cells and maintaining pluripotency in mES cell culture applications.	10 μg $199.00
Stemfactor™ Recombinant Mouse Wnt-5a , Cat. No. 03-0010 Stemfactor™ Recombinant Mouse Wnt-5a is a lyophilized recombinant protein purified from conditioned medium of L-Wnt-5a-expressing mouse fibroblast cells. It is a 38.6 kDa lipid-modified glycoprotein consisting of 343 amino acid residues. The preparation is tested for low endotoxin and biological activity. The biological activity is measured by inhibition of Wnt-3a induced alkaline phosphatase production in C3H/10T1/2 fibroblasts.	10 μg $299.00
Components
Stemfactor™ Epidermal Growth Factor (Human Recombinant) , Cat. No. 03-0003 Epidermal Growth Factor (EGF) is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation of a wide range of epidermal and epithelial cells.	100 μg $79.00
Stemfactor™ TGF-β1 (Human Recombinant) , Cat. No. 03-0004 Stemfactor™ TGF-β1, Human Recombinant, is a pleiotrophic growth factor that regulates proliferation and differentiation of many cells types including committed osteoblasts and human ES cells. Stemfactor™ TGF-β1 is expressed in human cells and induces IL-17 expression in TH17 cells as efficiently as TGF-β1 purified from platelets.	5 μg $189.00
Stemfactor™ Activin A (Human Recombinant) , Cat. No. 03-0001 Stemfactor™ Activin A is a crystallography-grade preparation providing the highest purity available. Activin A is bi-modal in action having been shown to maintain pluripotency of stem cells¹ and promote differentiation.²	5 ug $179.00
Stemfactor™ Noggin, Human Recombinant , Cat. No. 03-0006 Noggin, an antagonist of bone morphogenetic proteins (BMPs), allows human ES cells to maintain their undifferentiated, pluripotent state in a feeder-free medium supplemented with basic FGF.	10 μg $119.00
Stemfactor™ Fibroblast Growth Factor-basic (Human Recombinant) , Cat. No. 03-0002 Stemfactor™ Fibroblast Growth Factor-basic (Human Recombinant) bFGF is a critical component of embryonic stem cell culture medium because it is necessary for the cells to remain in an undifferentiated state.	50 μg $99.00
Transfection
Kits / Sets Components
Stemfect™ DNA Plasmid Transfection Polymer , Cat. No. 00-0001 Stemfect™ DNA Plasmid Transfection Polymer is a novel polymer specifically designed to transfect stem cells. It enables 2-5X improved transfection efficiency on stem cells compared to Lipofectamine™ 2000.¹	5 x 100 μl $199.00
Stemfect™ 2.0-mESC DNA Transfection Reagent , Cat. No. 00-0010 Stemfect™ 2.0-mESC DNA Transfection Reagent is a polymer-based transfection reagent specifically designed for in vitro DNA transfection of mouse embryonic stem (mES) cells. This reagent has demonstrated low cytotoxicity and 5X improved efficiency over leading transfection reagents in functional assays.	5 x 100 μl $269.00
Primary Cells
iPSC Generation Components
Stemgent® Oct4-neo MEF (P2) , Cat. No. 08-0014 Stemgent® Oct4-neo MEFs enable selection of induced pluripotent stem (iPS) cell colonies upon successful reprogramming. A neomycin resistant gene cassette was engineered into the endogenous Oct4 gene locus. When the reprogramming process is initiated, neomycin resistant gene will be expressed from the activation of the endogenous Oct4 gene. The iPS cells can then be selected in the presence of G418. Stemgent scientists have demonstrated iPS cell generation from the Stemgent® Oct4-neo MEFs.	~1.0E+06 cells per vial $499.00
Media
CellMates™ Accutase® Cell Detachment Solution , Cat. No. 01-0006 CellMates™ Accutase® Cell Detachment Solution contains no components of mammalian or bacterial origin and is far gentler on cell membranes than conventional trypsin solutions. It performs exceptionally well in detaching a variety of human cell types for multiple applications such as analysis of cell surface markers, cell proliferation, routine cell passage, production scale-up (bioreactor), and flow cytometry.	100 ml $19.00
Stemedia™ NutriStem™ XF/FF Culture Medium , Cat. No. 01-0005 Stemedia™ NutriStem™ XF/FF Culture Medium is a defined xeno-free, low growth factor human ESC/iPSC culture medium for a feeder-free culture environment that enables maintenance and expansion of pluripotent stem cells for multiple passages while retaining normal pluripotent marker expression, robust proliferation with a normal karyotype, and the ability to differentiate to cells of all three germ layers.	500 ml $169.00 100 ml $49.00
Stemedia™ Chem-D™ Culture Medium , Cat. No. 00-0048 Stemedia™ Chem-D™ Culture Medium is a chemically defined, serum-free human ESC/iPSC culture medium for a feeder-free culture environment that enables maintenance and expansion of human embryonic stem cells (hESC) as well as induced pluripotent stem cells (iPSC).	500 ml + 18.5 ml $169.00 100 ml + 3.7 ml $49.00
Stemedia™ WIT-T™ Culture Medium , Cat. No. 00-0047 Stemedia™ WIT-T™ Culture Medium offers optimized conditions for the culture of transformed human mammary epithelial cells for researchers and clinicians working in cancer/tumor biology. The cells grown in this media yield tumors that more closely resemble naturally occurring human adenocarcinomas than cells grown in other epithelial cell culture media.	100 ml + Supplements $79.00 500ml + Supplements $169.00
Stemedia™ WIT-P-NC™ Culture Medium , Cat. No. 00-0051 Stemedia™ WIT-P-NC™ Culture Medium is a serum-free, completely-defined medium for the robust culture of human breast primary epithelial cells (BPECs). BPECs proliferate far longer in WIT-P without the growth arrest typically seen using other culture medium, while maintaining a luminal epithelial-like state. Cells that are transformed from WIT-P-NC™ cultured BPECs give rise to tumors that more closely resemble actual human adenocarcinomas.	100 ml basal medium + 3 ml supplement $79.00 500 ml basal medium + 3 ml supplement $169.00
Stemedia™ WIT-P™ Culture Medium , Cat. No. 00-0045 Stemedia™ WIT-P™ Culture Medium is a serum-free, completely-defined medium for the robust culture of human breast primary epithelial cells (BPECs). BPECs proliferate far longer in WIT-P™ without the growth arrest typically seen using other culture medium, while maintaining a luminal epithelial-like state. Cells that are transformed from WIT-P™ cultured BPECs give rise to tumors that more closely resemble actual human adenocarcinomas.	100 ml + Supplements $79.00 500ml + Supplements $169.00
Stemedia™ WIT-I-NC™ Culture Medium , Cat. No. 00-0052 Stemedia™ WIT-I-NC™ Culture Medium is a serum-free, completely-defined medium optimized for the robust culture of human immortalized mammary epithelial cells (BPE). Cells cultured in Stemedia™ WIT-I-NC™ are maintained in a luminal epithelial-like state, and cells that are transformed from Stemedia ™ WIT-I-NC™ cultured BPEs give rise to tumors that closely resemble actual human adenocarcinomas.	100 ml basal medium + 3 ml supplement $79.00 500 ml basal medium + 3 ml supplement $169.00
Stemedia™ WIT-I™ Culture Medium , Cat. No. 00-0046 Stemedia™ WIT-I™ Culture Medium is a serum free, completely-defined medium optimized for the robust culture of human immortalized mammary epithelial cells (BPE). Cells cultured in WIT-I™ are maintained in a luminal epithelial-like state, and cells that are transformed from WIT-I™ cultured BPEs give rise to tumors that closely resemble actual human adenocarcinomas.	100 ml + Supplements $79.00 500ml + Supplements $169.00
CellMates™ Accumax™ Cell Dissociation Solution , Cat. No. 01-0007 CellMates™ Accumax™ Cell Dissociation Solution is a mixture of proteolytic and collagenolytic enzymes that performs exceptionally well in dissociating cell clumps in a variety of cell lines for multiple applications such as, cell counting, cell sorting, viral transfection assays, flow cytometry and bioreactor scale-up.	100 ml $49.00
Services
iPSC Generation
iPS Cell Line Generation Service , Cat. No. 10-0001 Stemgent® now offers a custom iPS cell line generation service providing researchers with an alternative to internal development of iPS cell lines. Using one of our viral, protein or chemical systems, we create iPS cell clones from your stable cell line or primary cells. Multiple primary iPS cell clones will be produced in as little as 3 months. Fully characterized iPS cell lines produced in as little as 6 months. Our staff can produce iPS cell clones at prices substantially less than many researchers can do in-house.	Call for Quote
iPSC Generation Kits / Sets
Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Mouse OSKM (conc) , Cat. No. ST000014-1Set The Stemgent® Dox Inducible Reprogramming Lentivirus: Mouse OKSM (conc.) provides an affordable inducible method for generating iPS cells. The set includes mOct4, mSox2, mc-Myc, and mKlf4 transcription factors along with reverse tetracycline transcriptional activator (rtTA) and GFP, prepackaged as lentivirus particles tested and proven to reprogram mouse somatic cells. Each unique virus is provided as a VSV-G pseudotyped and concentrated virus stock capable of infecting both dividing and non-dividing cells. The expression of the four transcription factors, in conjunction with rtTA, has been shown to direct a variety of differentiated cell types to become reprogrammed iPS cells.	1 set $3499.00
Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Mouse OKSM , Cat. No. ST000021-1Set The Stemgent^® Dox Inducible Reprogramming Lentivirus Set: Mouse OKSM provides an affordable inducible method for generating iPS cells. The set includes mOct4, mSox2, mc-Myc, mKlf4 transcription factors along with rtTA and GFP as prepackaged lentivirus particles tested and proven to reprogram mouse somatic cells.	1 set $1499.00
Stemgent^® Reprogramming Lentivirus Set: Human OSLN , Cat. No. ST000005-1Set The Stemgent^® Reprogramming Lentivirus Set: Human OSLN provides the human transcription factors Oct4, Sox2, Lin28 and Nanog for use in reprogramming somatic cells into an embryonic stem (ES) cell-like state known as the induced pluripotent stem (iPS) cell¹.	1 set $649.00

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Human IPSC Generation
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